It is known that standard antidepressants do not work for all. If they produce an effect, it takes a lot of time before it becomes noticeable. Fortunately, scientists at the University of California found the inhibitory activity of the enzyme GLO1 compound that reduces the symptoms of depression, writes “Orthodox”.
This proved an experiment with mice. Inhibition of the activity of GLO1 worked faster than the well-known antidepressant Prozac (a selective inhibitor of serotonin reuptake). With the new inhibitor and the symptoms disappeared in five days, and with the Prozac for 14 days.
In their work the researchers started with the knowledge about the special mechanism. So, cells generate energy. In the course of this process has a byproduct. This product inhibits the activity of neurons and affects behavior.
GLO1 enzyme normally removes this by-product. However, inhibition of GLO1 can be an amazing way to increase the activity of individual neurons. Thanks to the inhibitor mice became less anxious and they quickly disappeared symptoms of depression.